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Route, Selection and Advantages of Drug Administration

To administer a drug is to make the medicine accessible to the patient’s body where the effect is desired. The drug, therefore, is wanted by the Therapist to elicit or manifests an impact where it is desired. For this to occur, the drug should are available in contact with the tissues of organs and cells of muscles by one way or the other, the way the medication comes in contact or is made accessible to the tissue fluids tissues, cells, extracellular and intracellular fluids are the route of administration of the drug.

Selection of Route of Drug Administration:

1- Selection of Route of Drug Administration supported the method the drug is most fit for administration, i.e., supported the drug dosage forms. Medications are administered in various dosage forms: as reliable – e.g., oxytetracycline capsule — Paracetamol tablet Dimenhydrinate pill. As a solution – codeine syrup as suspension – insulin, penicillin procaine. Aerosol – beclomethasone Volatile liquid – halothane or nitrous oxide as ointments, lotions, pastes, etc.
Route, Selection and Advantages of Drug Administration

Route, Selection and Advantages of Drug Administration

2- Based on the characteristics of the drug, oil-based, organic. Polar, a non-polar solvent, etc.
3- The wanted bioavailability of the therapist.
4- the Wanted onset of action – how quick the therapist needs to see the visible outcome of the medication. This is necessary, particularly in life-threatening situations or conditions that require prompt onset of action are a shock, circulatory failure, the nature of the illness and its place of the state.
5- Duration of action – If a duration is expected to be extended; the drug is applied 2-4 times every day. This could be done in a depot form as a spot on the skin; another example is managing anaplasmosis, the aqueous oxytetracycline is administered 2-3 days by intramuscular, subcutaneous or intravenous dose. The long-acting oxytetracycline, which is indicated for slow absorption over 4-5 days.

PLACE OF DESIRED EFFECTS OF THE DRUG

Routes of drug administration:

The ways of medication administration for systemic impact may be classified into two main groups: Oral (enteral) and parenteral (systemic). When the GIT is bypass by medicine or introduction into the lungs. When the medication is the outcome is wanted locally it is administered topically, this is on the skin.

Oral Administration of Lungs:

Oral ingestion is the usual antique way of medication administration, another medium where the substance or medication to be administered is fixed in the rectum. Intravectally The potion could be put in the mouth, under the tongue. The drug could be delivered immediately into the stomach utilising intragastric tube.

Advantages:

  •  Safe
  • Sterility is no imperative
  • The risk of acute medication response is minimal

PARENTERAL ADMINISTRATION:

Parenterally “par” means beyond “enteral” means intestinal. This is the way of administration of a drug without passing the intestinal mucosa. This is probably when the drug is immediately into the blood or tissue fluid using a needle and syringe. It is necessary to note that the man that lead to the introduction of the hypodermic needle and syringe is Alexander wood. The common and most generally used parenteral routes are the intravenous route, intramuscular route and subcutaneous route respectively.

Other less frequent routes are:

Tissue infiltration, Intra articular, Intradermal, Epidural, Subaraclinord, Intra-arterial, Intrathecal, Intrathoracic, Intracardiac, Intramedullary, Intratesticular, Intralesional, Subconjuctival and Intramammary.

Advantages:

  1. Bioavailability is quicker and more likely.
  2.  Gastric irritation and vomiting are provoked.
  3. Parenteral routes could be used in unconscious, uncooperative and vomiting patient.
  4. There are no chances of resistance by diet or digestive enzymes.
  5. Liver enzymes are bypass.
  6. It is necessary seldom in the absorption of the effective form of the medication.
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